Detoxification Mechanisms in Fish -Regulation and Function of Biotransformation and Efflux in Fish Exposed to Pharmaceuticals and Other Pollutants
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منابع مشابه
Interspecies variation in the hepatic biotransformation of zearalenone: Evidence for bio-inactivation of mycoestrogen zearalenone in sturgeon fish
Zearalenone (ZEA) as mycoestrogen is found in human foods and animal feeds. Its estrogenic potency depends on its biotransformation fate. The hepatic biotransformation of ZEA in two species of sturgeon fish (Acipenser persicus and Huso huso) was investigated. ZEA was incubated with the hepatic microsomal and post-mitochondrial sub-fractions in the presence of NADPH and the metabolites were dete...
متن کاملInterspecies variation in the hepatic biotransformation of zearalenone: Evidence for bio-inactivation of mycoestrogen zearalenone in sturgeon fish
Zearalenone (ZEA) as mycoestrogen is found in human foods and animal feeds. Its estrogenic potency depends on its biotransformation fate. The hepatic biotransformation of ZEA in two species of sturgeon fish (Acipenser persicus and Huso huso) was investigated. ZEA was incubated with the hepatic microsomal and post-mitochondrial sub-fractions in the presence of NADPH and the metabolites were dete...
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The growth hormone in fish is involved in most of the physiological processes in the body, including the growth of soft and hard tissues, protein metabolism, lipid and carbohydrate, ionic regulation and osmotic balance, reproductive function, and immune system. Since the study on the use of growth hormone in ornamental fish is not available, the present study aims to regulate neuroendocrine gro...
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ATP-binding cassette (ABC) proteins were first recognized for their role in multidrug resistance (MDR) in chemotherapeutic treatments, which is a major impediment for the successful treatment of many forms of malignant tumors in humans. These proteins, highly conserved throughout vertebrate species, were later related to cellular detoxification and accounted as responsible for protecting aquati...
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Introduction: Micro pollutants have become one of the most important environmental concerns around the world. These natural and synthetic compounds have been called Endocrine Disrupting Chemicals (EDCs) due to their interfere with the normal function of the endocrine system in humans and animals. They include natural and synthetic hormones and their metabolites, surfactant, insecticide, as well...
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